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Impairment of blood formation is observed with a deficiency of vitamin B 12 in the organism—avitaminosis B 12, Addison-Biermer anemia (formerly called pernicious anemia), or malignant anemia. The cause of this type of anemia is impairment of the stomach’s output of a special protein, gastric mucoprotein (Castle’s intrinsic factor), which ensures absorption of vitamin B 12 in the intestine.
The Diamond Blackfan Anemia Foundation, Inc. (DBAF), founded in 1994, has adopted the following mission statement: “to advance research initiatives that promote a better understanding, therapeutic strategies and a cure for this rare bone marrow failure syndrome.
Diamond Blackfan Anemia The ICD-10-CM Alphabetical Index is designed to allow medical coders to look up various medical terms and connect them with the appropriate ICD codes. There are 0 terms under the parent term 'Diamond Blackfan Anemia' in the ICD-10-CM Alphabetical Index.
Diamond-Blackfan anemia (DBA) is characterized by red cell failure, the presence of congenital anomalies, and cancer predisposition. In addition to being an inherited bone marrow failure syndrome, DBA is also categorized as a ribosomopathy as, in more than 50% of cases, the syndrome appears to result from haploinsufficiency of either a small or large subunit-associated ribosomal protein.
Diamond Blackfan anaemia (DBA) is a rare, genetically and clinically heterogeneous, inherited red cell aplasia. Classical DBA affects about seven per million live births and presents during the first year of life.
The Diamond-Blackfan anemia was named for Dr. Louis K. Diamond and Dr. Kenneth D. Blackfan, the first doctors who documented cases of the disease in the 1930s. Diamond-Blackfan anemia affects approximately 5 to 7 per million liveborn infants worldwide.
The term 'incidence' of Diamond-Blackfan anemia refers to the annual diagnosis rate, or the number of new cases of Diamond-Blackfan anemia diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence.